Which long-term health effects are highly associated with a diagnosis of anorexia nervosa?

Ever wonder what happens when your body doesn’t get the fuel it needs for months or years on end? ðŸ§
Anorexia nervosa isn’t just about weight loss or body image – it’s a serious mental health condition that wages war on nearly every system in your body.
While there are many health consequences of anorexia (and we’ll cover them all), one stands out as particularly devastating and long-lasting: bone loss.
Let’s dive into why this happens, what it means for long-term health, and what other systems get caught in the crossfire of this complex disorder.
Bone Health: The Silent Casualty

When it comes to long-term health effects, bone damage tops the list for anorexia patients. Here’s why:
- Nearly 90% of women with anorexia develop a condition called osteopenia, which means a significant loss of bone calcium
- Up to 40% of people with anorexia face full-blown osteoporosis, an advanced loss of bone density that makes bones fragile and prone to breaking
- More than two-thirds of adolescent girls with anorexia don’t develop strong bones during their critical growth periods
The scary part? Some of this bone loss can be irreversible, even after recovery and weight restoration.
Think of it this way: your teenage and young adult years are like the “bone bank” deposit period. If you’re not depositing calcium and other minerals during this critical window because of anorexia, you might never catch up – leaving you with a “bone bankruptcy” that lasts a lifetime.
Why Does Anorexia Attack Your Bones?
The connection between anorexia and bone health is a perfect storm of multiple factors:
- Estrogen deficiency – The severe calorie restriction in anorexia leads to low estrogen levels, which is critical for maintaining bone density
- Low body weight – Less weight-bearing pressure on bones means less stimulation for bone growth
- Elevated cortisol levels – Chronic stress and malnutrition increase cortisol, which actively breaks down bone tissue
- Nutritional deficiencies – Lack of calcium, vitamin D, and protein all compromise bone integrity
This bone loss isn’t just a cosmetic concern – it creates a three to seven-fold increased risk of spontaneous fractures according to research published on PubMed.
Imagine being in your 30s or 40s with the bone density of someone in their 70s or 80s. That’s the reality for many people who have battled long-term anorexia.
The Cardiovascular System: Another Major Casualty

While bone health might be the most common long-term effect, heart damage is arguably the most immediately life-threatening:
- 80% of anorexia patients experience cardiac complications
- Sinus bradycardia (abnormally slow heart rate) becomes the norm rather than the exception
- Prolonged QT interval on electrocardiograms increases the risk of sudden cardiac death
- Structural changes to the heart muscle itself can occur, including decreased heart mass
The heart literally shrinks and weakens in response to starvation. It’s like asking a car to run on fumes – eventually, the engine starts breaking down. 🚗
Fertility and Reproductive Health
For many people with anorexia, the long-term impact on fertility comes as a devastating surprise:
- Amenorrhea (loss of menstrual periods) is common during active anorexia, but fertility problems can persist even after weight restoration
- Higher rates of pregnancy complications including hyperemesis gravidarum, anemia, and poor fetal growth
- Unplanned pregnancies are actually more common among women with histories of anorexia, possibly due to the misconception that they cannot get pregnant
This is particularly heartbreaking because many people aren’t warned about these potential long-term effects when they’re in the depths of the disorder.
The Digestive System: Permanent Changes

Your digestive system doesn’t escape unscathed either:
- Gastroparesis (delayed stomach emptying) can become chronic, leading to bloating, nausea, and early fullness
- Cathartic colon from laxative abuse can cause permanent damage to the intestines
- Malabsorption issues may persist even after recovery, making it harder to get nutrients from food
These digestive issues create a cruel irony – they can make the recovery process itself more physically uncomfortable, potentially triggering relapse.
Psychological Effects That Linger

The mental and emotional scars of anorexia can last long after physical recovery:
- Depression and anxiety often become chronic companions
- Cognitive changes including difficulty concentrating and memory problems
- Increased suicide risk – studies show that women with anorexia have a suicide risk 57 times higher than women without the disorder
The brain itself can undergo structural changes during prolonged malnutrition, some of which may not fully reverse with recovery.
The Mortality Reality Check
It’s impossible to talk about long-term effects without acknowledging the most serious one: anorexia has the highest mortality rate of any psychiatric disorder, second only to opioid overdose.
- 5.86 standardized mortality ratio – meaning people with anorexia are nearly 6 times more likely to die than their peers
- 1 in 5 anorexia deaths are by suicide
- Over 2,600 additional deaths per year in the US alone are attributed to anorexia
These aren’t just statistics – they’re lives cut short by a treatable condition.
Early Intervention: The Key to Preventing Long-Term Damage
The timeline for detection, intervention, and treatment is crucial for preventing these long-term health effects. The longer anorexia persists, the more entrenched and potentially permanent the damage becomes.
If you’re concerned about yourself or a loved one, check out our articles on recognizing the early signs of eating disorders and effective treatment approaches for anorexia.
The Bottom Line
While bone loss stands out as the most common and potentially irreversible long-term health effect of anorexia, the truth is that this disorder doesn’t play favorites with body systems – it attacks them all.
The good news? Many of these effects can improve or even resolve with proper treatment and sustained recovery. The human body has remarkable healing capabilities when given the chance.
But the key message here is clear: anorexia isn’t just about weight or food – it’s a serious medical condition with potentially lifelong consequences. The sooner treatment begins, the better the chances of preventing these long-term health effects.
Recovery isn’t just possible – it’s essential. 💪